Human CD47, also known as leukocyte surface antigen CD47, Rh-related antigen, integrin-associated protein (IAP), antigenic surface determinant protein OA3, and MER6. GenBank Accession No. NM_001777, a.a. 19-139 fused at the C-terminus to the Fc portion of human IgG1 and C-terminal Avi-tag expressed in a HEK293 cell expression system and enzymatically biotin-labeled using Avi-tag™ technology. MW = 42.2 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.

Q08722

leukocyte surface antigen CD47, Rh-related antigen, CD47, CD-47, integrin-associated protein (IAP), antigenic surface determinant protein OA3, and MER6

8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol

Aqueous buffer solution

At least 6 months at -80°C (for all proteins)

Useful for the study of protein-protein interaction and in vitro and in vivo protein function studies.

1. Vernon-Wilson, E.F., et al., Eur. J. Immunol. 2000; 30(8): 2130-2137.
2. Majeti, R. et al., Cell. 2009; 138(2): 286-299.

HiP™ indicates a high purity protein with ≥90% purity as measured by gel filtration.

Avoid freeze/thaw cycles. Protein may be diluted to 100 μg/ml in PBS + glycerol and stored at -80°C.

Immunotherapy

Recombinant Protein