Human Bromodomain SMARCA2, also known as BRM, GenBank Accession No. NM_003070, a.a. 1375 – 1511 corresponding to single bromodomain with N-terminal His-tag, MW = 16.9 kDa, expressed in an E. coli expression system.

P51531

SMARCA2, BRM, BRG1-Associated Factor 190B, SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin 2, BAF190, SNF2L2

40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04 % Tween-20, 20% glycerol

Aqueous buffer solution

>6 months at –80°C.

Useful for the study of bromodomain binding assays, screening inhibitors, and selectivity profiling.

1. Shain, A.H., et al., Proc Natl Acad Sci USA. 2012 Jan 31; 109(5): E252-9.
2. Liu, G., et al., Oncogene. 2011 Jul 21; 30(29): 3295-304

Avoid freeze/thaw cycles.

MHHHHHHKLSPNPPKLTKQMNAIIDTVINYKDRCNVEKVP
SNSQLEIEGNSSGRQLSEVFIQLPSRKELPEYYELIRKPV
DFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQ
IYEDSIVLQSVFKSARQKIAKEEE

Bromodomain

Recombinant Protein