Human bromodomain E1A binding protein p300, also known as EP300, KAT3B, or RSTS2, GenBank Accession No. NM_001429, a.a. 1046-1163 corresponding to single bromodomain with N-terminal His-tag, MW=15.1 kDa, expressed in an E. coli expression system.

Q09472

EP300, KAT3B, RSTS2, E1A binding protein, cbp

40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.

Aqueous buffer solution

>6 months at –80°C.

Useful for the study of bromodomain binding assays, screening inhibitors, and selectivity profiling.

1. Gui, Y., et al., Nat. Genet. 2011 Aug 7; 43(9) : 875 – 878.
2. Morin, R.D., et al., Nature. 2011 Jul 27; 476(7360) : 298 – 303.
3. Zhao, Z., et al., Brain Res. Bull. 2011 Oct 10; 86(3-4) : 189 – 194.

Avoid freeze/thaw cycles.

Bromodomain

Recombinant Protein