| 产品名称 | Bromosporine |
| 产品货号 | 27612 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 1 mg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
MW: 404.4 Da
Formula: C17H20N6O4S
Background: Bromodomains have an important role in the targeting of chromatin-modifying enzymes to specific sites, including methyltransferases, HATs and transcription factors and regulate diverse biological processes from cell proliferation and differentiation to energy homeostasis and neurological processes.
Description: Bromosporine is a broad spectrum inhibitor for bromodomains.
Synonym(s): ethyl (3-methyl-6-(4-methyl-3-(methylsulfonamido)phenyl)-[1,2,4]triazolo[4,3-b]pyridazin-8-yl)carbamate
Biological Activity: Bromosporine exhibits IC50 values of 0.41 µM, 0.29 µM, 0.122 µM and 0.017 µM for BRD2, BRD4, BRD9 and CECR2, respectively.
Solubility: Soluble in DMSO (100 mM) and ethanol (25 mM)
Storage / Stability: Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day. Reference(s): Gallenkamp et al. (2014). Chem Med Chem 9:438.
Scientific Category: Bromodomain Inhibitor
Product Type: Inhibitor
Data shown is lot-specific. Contact us for specific information on other lots.
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