Anti-human CD73 recombinant Murine/Human chimeric antagonist antibody. This antibody not been tested for cross reactivity with other species.

NT5E, CALJA, E5NT, NT

Protein A affinity purification from HEK293 supernatants.

Aqueous buffer solution.

40 mM Tris-HCl pH 8.0, 110 mM NaCl, 2.2 mM KCl and 20% glycerol.

Stable for at least 12 months at -80°C

Targeting CD73 has been shown to prevent tumor recurrence and metastases in cancer patients. Anti-CD73 antibodies have been suggested as a new form of personalized cancer therapy.

1. Deaglio, S. et al., J. Exp. Med. 2007;204(6): 1257-1265.

2. Thompson, L.F., et al., J. Exp. Med. 2004; 200(11): 1395.

Avoid multiple freeze/thaw cycles.

Immunotherapy

Antibody