Neutralizing recombinant human monoclonal antibody recognizing the extracellular domain of CTLA4 and blocking binding of CTLA4 to B7.1 and B7.2. This antibody recognizes human CTLA4 but does not bind to murine CTLA4. This antibody has not been tested for cross-reactivity with other species
| 产品名称 | Anti-CTLA4 Neutralizing Antibody - Neutralizing Antibodies - Antibodies |
| 产品货号 | 71212 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 100 µg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
Species: Human
Host Species: Freestyle 293 cells
MW: 150 kDa
Isotype: IgG1κ
Description: Synonym(s): Cytotoxic T-lymphocyte-associated protein 4, CD152
Endotoxin Level: <1 EU/µg
Specific Activity: IC50 = 5 nM
Assay Conditions: Antibody was added to
CTLA4:B7.1 binding assay at various
concentrations. Assay was done according to
BPS Cat. #72009 protocol.
Formulation: 8 mM phosphate, 110 mM
NaCl, 2.2 mM KCl, pH 7.4, and 20%
glycerol
Purification: Protein A affinity chromatography
from HEK293 supernatants.
Format: Aqueous buffer solution.
Storage / Stability: Stable for at least 12 months at
-80°C.
Application(s): Useful for inhibition of CTLA4:B7 interactions.
Reference(s): 1. Linsley, P.S., et al., J. Exp. Med. 1991; 174(3): 561-569. Warning(s): Avoid freeze/thaw cycles. Store
diluted antibody with carrier protein (BSA
0.1 – 0.5%) at 4°C, stable for 2 weeks.
Scientific Category: Immunotherapy
Product Type: Antibody
Data shown is lot-specific. Contact us for specific information on other lots.
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