| 产品名称 | DNA Polymerase β (POLB), His-tag |
| 产品货号 | 21000-1 21000-2 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 100 µg 1 mg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
Species: Human
Host Species: E. coli
MW: 39 kDa
Genbank #: NM_002690
Tag(s): N-terminal His-tag
a.a: 2–335 (end)
Background: DNA polymerase involved in base excision and repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the
3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. The protein is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage.
Description: Human DNA polymerase β (beta), also known as Pol beta and POLB (GenBank Accession No. NM_002690), a.a. 2-335 (end), with N-terminal His-tag, MW=39 kDa, expressed in an E. coli cell expression system.
Synonym(s): DNA polymerase beta, Pol beta and POLB
Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 250 mM imidazole, 0.04% Tween-20, and 20% glycerol.
Format: Aqueous buffer solution
Application(s): Useful for DNA synthesis and DNA repair, as an antigen for Western blotting, and for inhibitor screening.
Reference(s): 1. Yamtich, J., et al., PLoS Genet. 2012,8(11): E1003052. Warning(s): Avoid freeze/thaw cycles
Scientific Category: Molecular Biology
Product Type: Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
|
| 产品资料 |
