Human secreted KYNU, also known as Kynureninase and L-Kynurenine hydrolase, with C-terminal His-Tag. GenBank Accession No. NM_003937, a.a. 1-465 (end), expressed in Sf9 cells in a Baculovirus expression system. MW = 53 kDa.

Kynureninase, L-Kynurenine hydrolase

≥75 pmol/min/µg

1.341 mg/ml

40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween20, 20% glycerol, 225mM imidazole, 2uM PLP, 2µM DTT

At least 6 months at –80°C

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

1. Christensen, M., et al., JIMD. 2007 Mar: 248-255.

2. Zhang, Y., et al., Circ Genom Precis Med. 2018; 11(3).

Avoid freeze/thaw cycles. Protein may be diluted to ≥ 100 µg/ml in PBS + glycerol and stored at -80°C.

Immunotherapy

Protein