Monkey Signal regulatory protein-alpha (SIRP-α), also known as Tyrosine-protein phosphatase non-receptor type substrate 1, CD172a, Bit, and MyD-1, GenBank Accession No. NM_001284750, a.a. 31-370, with C-terminal Avi-His-tag, expressed in a HEK293 expression system. MW=42 kDa. The protein is enzymatically biotinylated using AviTag™ technology. This protein is heavily glycosylated, resulting in apparent higher molecular weight.

Tyrosine-Protein Phosphatase Non-Receptor Type Substrate 1, CD172a, Bit, and MyD-1

8mM phosphate, 110mM NaCl, 2.2mM KCl, pH7.4, and 20% glycerol.

Aqueous buffer solution.

At least 6 months at –80°C.

1. Hatherley, D., et al., Mol. Cell, 2008, 31:266-77

2. Baba, N., et al., J. Exp. Med., 2013, 210(6):1251-63

HiP™ indicates a high purity protein with ≥90% purity as measured by gel filtration.

Avoid freeze/thaw cycles. Protein may be diluted to ≥ 100 µg/ml in PBS + glycerol and stored at -80°C.

Immunotherapy

Recombinant Protein