Mouse secreted Programmed Cell Death 1 Ligand 1 (PD-L1)-Fc fusion protein, also known as CD274 and B7 homolog 1 (B7- H1), GenBank Accession No. NM_021893, a.a. 19-238, fused at the C-terminus to the Fc portion of mouse IgG2a, expressed in a HEK293 cell expression system. MW = 51.8 kDa.

Q9EP73

Programmed Cell Death 1 Ligand 1, CD274, B7 homolog 1 (B7-H1)

8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.

Aqueous buffer solution

At least 6 months at –80°C.

Useful for the study of protein-protein interaction and in vitro and in vivo protein function studies.

1. Freeman, G.J., et al., J. Exp. Med. 2000; 192(7):1027-34.
2. Dong, H., et al., Nat. Med. 1999; 5(12):1365-9.

Product Specific Reference(s): 
1. Lmai, Y., et al., J. Immunol. 2015; 195(2): 421-425. 

HiP™ indicates a high purity protein with ≥90% purity as measured by gel filtration.

Avoid freeze/thaw cycles. Storing diluted protein is not recommended, if necessary, use carrier protein (BSA 0.1 – 0.5%).

Immunotherapy

Recombinant protein