Human NLR Family Pyrin Domain Containing 3 (NLRP3), also known as NALP3, Cold Autoinflammatory Syndrome 1 Protein (CIAS1), cryopyrin and PYPAF1, with K232A mutation, (Genbank Accession No. NM_004895), a.a. 2-1036(end) with N-terminal His-FLAG-tag, expressed in a baculovirus infected Sf9 cell expression system. MW = 120 kDa (calculated).

NLR Family Pyrin Domain Containing 3, NLRP3, Cold Autoinflammatory Syndrome 1 Protein (CIAS1), cryopyrin, PYPAF1, NALP3

40mM Tris-HCl, pH 8.0, 110mM NaCl, 2.2mM KCl, 0.04% Tween-20, 100µg/ml FLAG peptide and 20% glycerol.

Aqueous buffer solution

At least 6 months at –80°C. Avoid freeze/thaw cycles. Protein may be diluted to ≥ 100 µg/ml in PBS + glycerol and stored at -80°C.

1. Kummer, J.A., J. Histochem. Cytochem., 2007 May; 55(5):443-52.
2. Manji, G.A., J. Biol. Chem. 2002 Mar 29; 277(13):11570-5.

 

Immunotherapy

Recombinant Protein