Human FCGR3A, known as Fc gamma RIIIA, and CD16a with F176V mutation, GenBank Accession No. NM_001127593.1, a.a. 17-208, with N-terminal AviTM-His-Tag, expressed in a HEK293 cell expression system. This protein runs at a higher MW by SDS-PAGE due to glycosylation. MW = 25 kDa.

Fc gamma RIIIA, CD16a with F176V mutation

8mM phosphate, pH 7.4, 110mM NaCl, 2.2mM KCl, and 20% glycerol.

Aqueous buffer solution

At least 6 months at –80°C

1. Zhang, W., et al., Journal of Clinical Oncology. 2007; 25(24): 3712-3718.

2. Dall’Ozzo, S., et al., Cancer Research. 2004; 64(13): 4664-4669.

Avoid freeze/thaw cycles

Immunotherapy

Protein