Human CD47, Fc fusion protein, also known as leukocyte surface antigen CD47, Rh-related antigen, integrin-associated protein, antigenic surface determinant protein OA3, antigen identified by monoclonal antibody 1D8, and MER6. GenBank Accession No. NM_001777, a.a. 19-139 fused at the C-terminus to the Fc portion of human IgG1, expressed in a HEK293 cell expression system. MW = 40 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.

Q08772

leukocyte surface antigen CD47, Rh-related antigen, integrin-associated protein, antigenic surface determinant protein OA3, antigen identified by monoclonal antibody 1D8, MER6.

8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.

Aqueous buffer solution

At least 6 months at –80°C.

Useful for studying protein binding and for screening small molecules and antibodies.

1. Vernon-Wilson, E.F. et al., Eur. J. Immunol. 2000; 30(8): 2130-2137.
2. Majeti, R. et al., Cell. 2009; 138(2): 286- 299.

Avoid freeze/thaw cycles.

Immunotherapy

Recombinant Protein