Human secreted CD2-Fc fusion protein, also known as LFA-2, GenBank Accession No. NM_001767, a.a. 25-209, fused at the C-terminus to the Fc portion of human IgG1, with C-terminal Avi-tag, expressed in a HEK293 cell expression system and enzymatically biotin-labeled using Avi-tag technology. MW = 50 kDa (monomer). This protein runs at a higher M.W. by SDS-PAGE due to glycosylation.

CD2

2.09 mg/ml

8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.

At least 6 months at –80°C. Avoid freeze/thaw cycles. Protein may be diluted to ≥ 100 µg/ml in PBS + glycerol and stored at -80°C.

Useful for the study of protein-protein interaction and in vitro and in vivo protein function studies.

1. Seed, B., et al., Nature. 1987 Oct; 329: 840-842.

2. Seed, B., et al., PNAS. 1987 May; 84: 3365-3369.

HiP™ indicates a high purity protein with ≥90% purity as measured by gel filtration.

Immunotherapy

Protein