| 产品名称 | PPID (CYP-40), GST-tag |
| 产品货号 | 71095 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 100 µg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
Species: Human
Host Species: E. coli
MW: 67.5 kDa
Genbank #: NM_005038
Tag(s): N-terminal GST-tag
a.a: 2–370(end)
Background: PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein has been shown to possess PPIase activity and, similar to other family members, can bind to the immunosuppressant cyclosporin A. Proposed to act as a co-chaperone in HSP90 complexes. Promotes cell viability in anaplastic lymphoma kinase-positive anaplastic large-cell lymphoma (ALK+ ALCL) cell lines. May be involved in hepatitis C virus (HCV) replication and release.
Description: Human Peptidyl-prolyl cis-trans isomerase D (PPID), also known as peptidyl-prolyl cis-trans isomerase Cyclophilin-40 (CYP-40, CyP-D), GenBank Accession No. NM_005038, a.a. 2-370(end), with N-terminal GST-tag, MW 67.5 kDa, expressed in an E. coli cell expression system.
UniProt Q08752
Synonym(s): Peptidyl-prolyl cis-trans isomerase D, PPID, peptidyl-prolyl cis-trans isomerase, Cyclophilin-40, CYP-40, CyP-D, Rotamase D
Formulation: 40 mM Tris-HCl pH 8.0, 110 mM NaCl, 2.2 mM KCl, 16 mM glutathione, and 20% glycerol.
Format: Aqueous buffer solution
Storage / Stability: >6 months at –80°C Application(s): Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Reference(s): 1. Tavecchio, M., et al., J. Biol. Chem. 2013;288(8):5553-5561.
2. Ward, B.K., et al., J. Biol. Chem. 2002;277(43):40799-40809. Warning(s): Avoid freeze/thaw cycles
Scientific Category: Metabolic Enzymes-Transferase
Product Type: Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
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