Human TGFβ1 (GenBank Accession #NM_000660), a.a. 279-390(end), forms a disulfide-linked homodimer of 25 kDa (Monomer MW = 13 kDa).

P01137

TGFB1, transforming growth factor beta 1, TGFbeta1, TGFβ1

≥95% by SDS-PAGE

< 1EU per µg

The ED50 measured by TGFβ1’s ability to inhibit mIL-4-dependent proliferation of HT-2 mouse helper T cells is <0.05ng/ml.

Lyophilized from a 0.2 µm filtered, aqueous solution

lyophilized protein

Reconstitute in sterile dH20.

>6 months at –80°C (as a solid). Store reconstituted protein in aliquots at –80°C for up to 3 months. Avoid freeze/thaw cycles.

Useful for cell culture and for the study of signaling and apoptotic pathways.

1. Derynck, R. et al. (1985). Nature 316(6030):701-5.
2. Bourdrel L., et al. (1993). Protein Expr. Purif. 4:130-140.
3. Munger, J.S., et al. (1997). Kidney Int. 51:1376-1382.

Avoid freeze/thaw cycles.

Cytokine/Growth Factors

Recombinant Protein