产品名称 Mouse Exodus-2 - Cytokine(s)
产品货号 90131-A
产品价格 现货询价,电话:010-67529703
产品规格 5 µg
产品品牌 bpsbioscience
产品概述
产品详情
Species: Mouse
Host Species: E. coli
MW: 12 kDa
Genbank #: P84444
a.a: 24–133
Background:
Exodus-2, which is a member of the family of CC- Chemokines, has a unique 36 (murine) or 37 (human) amino acid carboxyl-terminal extension not seen in other chemokines. Exodus-2 selectively stimulates the chemotaxis of adult T-lymphocytes and is expressed preferentially in lymph node tissue. Exodus-2 is critical for adult T-cell adhesion to high endothelial venules in lymph nodes, a rate-limiting step for T-cell trafficking through nodal tissue.
Description:
Recombinant mouse Exodus-2 is a disulfide-linked homodimeric protein consisting of 111 amino acid residues, and migrates as an approximately 12 kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding murine Exodus-2 mature chain was expressed in E. coli.
UniProt
P84444
Synonym(s):
CCL21, SCYA21, Exodus-2
Purity:
≥95% by SDS-PAGE and HPLC
Endotoxin Level:
<0.1 ng/µg (1 EU/µg), using the LAL gel clot method.
Biological Activity:
Determined by its ability to chemoattract total lymphocyte population using a concentration range of 10.0-100.0 ng/ml.
Formulation:
Lyophilized from 0.2 µm filtered PBS solution.
Format:
lyophilized protein
Reconstitution:
Reconstitute at 0.1-1.0 mg/ml in distilled water. This solution can then be diluted into other buffers. To maximize product collection from vial surface, vortex briefly and then spin down to recollect the liquid.
Storage / Stability:

The lyophilized protein is stable for at least 2 years from date of receipt when stored at -20°C. Upon reconstitution, store in working aliquots at +4°C for up to one month, or at -20°C for up to six months, in the presence of a carrier protein. Avoid repeated freeze/thaw cycles.

Reference(s):
J. Exp. Med., Jan 2000, 191: 61.
Warning(s):
Avoid freeze/thaw cycles
Amino Acid Sequence:
SDGGGQD CCLKYSQKKI PYSIVRGYRK QEPSLGCPIPAILFSPRKHS KPELCANPEE GWVQNLMRRL DQPPAPGKQS PGCRKNRGTS KSGKKGKGSKGCKRTEQTQP SRG
Scientific Category:
Cytokine/Growth Factors
Product Type:
Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.

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