| 产品名称 | Human TARC(CCL17) - Cytokine(s) |
| 产品货号 | 90241-B |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 20 µg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
Species: Human
Host Species: E. coli
MW: 8 kDa
Genbank #: Q92583
a.a: 24–94
Background: Thymus and activation-regulated chemokine (TARC) is a recently identified CC chemokine that is expressed constitutively in thymus and transiently in stimulated peripheral blood mononuclear cells. TARC functions as a selective chemoattractant for T-cells that express a class of high affinity receptors binding TARC. The chemokine TARC is a ligand for the chemokine receptor CCR4 expressed on T helper (Th)2- type CD4 T cells.
Description: Recombinant TARC (CCL17) is a disulfide-linked monomeric protein consisting of 72 amino acid residues and migrates as an approximately 8 kDa protein under non-reducing conditions and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human TARC (CCL17) mature chain was expressed in E. coli.
UniProt Q92583
Synonym(s): TARC, CCL17, Thymus and activation-regulated chemokine, ABCD-2
Purity: ≥98% by SDS-PAGE and HPLC
Endotoxin Level: <0.1 ng/µg (1 EU/µg), using the LAL gel clot method.
Biological Activity: Determined by its ability to chemoattract human T cells using a concentration range of 2.0-40.0 ng/ml.
Formulation: Lyophilized from a 0.2 µm filtered 20 mM phosphate buffer, 100 mM NaCl solution, pH 7.5.
Format: lyophilized protein
Reconstitution: Reconstitute at 0.1-1.0 mg/ml in distilled water. This solution can then be diluted into other buffers. To maximize product collection from vial surface, vortex briefly and then spin down to recollect the liquid.
Storage / Stability: The lyophilized protein is stable for at least 2 years from date of receipt when stored at -20°C. Upon reconstitution, store in working aliquots at +4°C for up to one month, or at -20°C for up to six months, in the presence of a carrier protein. Avoid repeated freeze/thaw cycles. Reference(s): 1. Saeki H, Tamaki K. J Dermatol Sci. 2006 Aug,43(2):75-84.
2. Biragyn A, et al. J Immunother. 2013 May,36(4):258-67. Warning(s): Avoid freeze/thaw cycles
Amino Acid Sequence: RGTNVGRECCLEYFKGAIPLRKLKTWYQTSEDCSRDAIVFVTVQGRAICSDPNNKRVKNAVKYLQSLERS
Scientific Category: Cytokine/Growth Factors
Product Type: Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
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