产品名称 Human Fibroblast Growth Factor 21 - Cytokine(s)
产品货号 90134-A
产品价格 现货询价,电话:010-67529703
产品规格 5 µg
产品品牌 bpsbioscience
产品概述
产品详情
Species: Human
Host Species: E. coli
MW: 20 kDa
Genbank #: Q9NSA1
a.a: 29–209
Background:
FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-21 stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB.
Description:
Recombinant Fibroblast Growth Factor 21 is a disulfide-linked monomer protein consisting of 182 amino acid residues, and migrates as an approximately 20 kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human Fibroblast Growth Factor-21 mature chain was expressed in E. coli.
UniProt
Q9NSA1
Synonym(s):
FGF-21, Fibroblast Growth Factor-21
Purity:
≥96% by SDS-PAGE and HPLC
Endotoxin Level:
<0.1 ng/µg (1 EU/µg), using the LAL gel clot method.
Formulation:
Lyophilized from 0.2 µm filtered PBS solution, pH 7.0.
Format:
lyophilized protein
Reconstitution:
Reconstitute at 0.1-1.0 mg/ml in distilled water. This solution can then be diluted into other buffers. To maximize product collection from vial surface, vortex briefly and then spin down to recollect the liquid.
Storage / Stability:

The lyophilized protein is stable for at least 2 years from date of receipt when stored at -20°C. Upon reconstitution, store in working aliquots at +4°C for up to one month, or at -20°C for up to six months, in the presence of a carrier protein. Avoid repeated freeze/thaw cycles.

Reference(s):
1. Teillon, S., et al. J Endocrinol. 2010 Apr,205(1):37-47.
2. Suzuki, M., et al. Mol. Endocrinol., Apr 2008, 22: 1006 - 1014.
Warning(s):
Avoid freeze/thaw cycles
Amino Acid Sequence:
HP IPDSSPLLQF GGQVRQRYLY TDDAQQTEAH LEIREDGTVG GAADQSPESL LQLKALKPGV IQILGVKTSR FLCQRPDGAL YGSLHFDPEA CSFRELLLED GYNVYQSEAH GLPLHLPGNK SPHRDPAPRG PARFLPLPGL PPALPEPPGI LAPQPPDVGS SDPLSMVGPS QGRSPSYAS
Scientific Category:
Cytokine/Growth Factors
Product Type:
Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.

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产品资料