| 产品名称 | Human Eotaxin-3(CCL26) - Cytokine(s) |
| 产品货号 | 90129-B |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 20 µg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
Species: Human
Host Species: E. coli
MW: 9 kDa
Genbank #: Q9Y258
a.a: 24–94
Background: Eotaxin belongs to the platelet factor-4 family of chemokines. The factor is being referred to also as Eotaxin-2 and has been renamed CCL24. Both eotaxin-2/CCL24 and eotaxin-3/CCL26 are CC chemokines and functional ligands for CC chemokine receptor 3 (CCR3), which is preferentially expressed on eosinophils. Only 34% of the amino acids in eotaxin-2/CCL24 and eotaxin-3/CCL26 are identical, but these two chemokines have a common characteristic feature in terms of chemotaxis for eosinophils via the CCR3.
Description: Recombinant Eotaxin-3 is a disulfide-linked homodimeric protein consisting of 72 amino acid residues, and migrates as an approximately 9 kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding human Eotaxin-3 mature chain was expressed in E. coli.
UniProt Q9Y258
Synonym(s): CCL26, Eotaxin-6, SCYA26, Thymic Stroma Chemokine-1, TSC-1, IMAC, MIP-4alpha, MIP4a
Purity: ≥97% by SDS-PAGE and HPLC
Endotoxin Level: <0.1 ng/µg (1 EU/µg), using the LAL gel clot method.
Biological Activity: Biological activity was determined by the ability to induce chemotaxis of purified eosinophils at concentrations ranging between 50-100 ng/ml.
Formulation: Lyophilized from 0.2 µm filtered PBS, pH 7.5 with 10% glycerol.
Format: lyophilized protein
Reconstitution: Reconstitute at 0.1-1.0 mg/ml in distilled water. This solution can then be diluted into other buffers. To maximize product collection from vial surface, vortex briefly and then spin down to recollect the liquid.
Storage / Stability: The lyophilized protein is stable for at least 2 years from date of receipt when stored at -20°C. Upon reconstitution, store in working aliquots at +4°C for up to one month, or at -20°C for up to six months, in the presence of a carrier protein. Avoid repeated freeze/thaw cycles. Reference(s): 1. J Rheumatol, Aug 2009, 36: 1590 - 1595.
2. Rheumatology, Jun 2008, 47: 804 - 808. 3. Eur. Respir. J., Nov 2005, 26: 795 - 803. Warning(s): Avoid freeze/thaw cycles
Amino Acid Sequence: TRGSDIS KTCCFQYSHK PLPWTWVRSY EFTSNSCSQR AVIFTTKRGK KVCTHPRKKW VQKYISLLKT PKQL
Scientific Category: Cytokine/Growth Factors
Product Type: Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
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