Recombinant human Anti-OX40 competitive antibody recognizing the OX40 binding region. This antibody has not been tested for cross-reactivity with any other species.

tumor necrosis factor ligand superfamily member 4, TNFSF4, CD252, TNF Receptor Superfamily Member 4, TRAF2

Reaction done according to OX40[biotin]-OX40L assay kit (Catalog # 72045). Buffer is PBS + 0.1% BSA. Blocking buffer is Superblock + 0.05% Tween-20. Coat protein was added ON at 4 degrees. Inhibitor and then biotinylated ligand added for 2 hours at room temperature. Strep-HRP added for 1 hour at room temperature.

8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.

Aqueous buffer solution

Stable for at least 12 months at -80°C.

Useful for the inhibition of OX40:OX40L interactions.

1. Garrison, K., et al., Cancer Immunology. 2012 April; 61(4): 511-521.

2. Bulliard, Y., et al., Immunology & Cell Biology. 2014 Apr; 92: 475-480.

The aggregation state of this product has been confirmed to be <10%

Protect from light. Avoid freeze/thaw cycles. Store diluted antibody with carrier protein (BSA 0.1 – 0.5%) at 4°C, stable for 2 weeks.

Immunotherapy

Antibody