Human FGFR3, GenBank Accession # NM_000142, with V443L mutation, with N-terminal His-tag, a.a 447-761, MW= 37 kDa, expressed in Sf9 cells via a baculovirus expression system. Phosphorylation is <10%.

P22607

Fibroblast growth factor receptor 3, FGFR3, JTK4

40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.02% Tween, 20% glycerol, 3mM DTT.

Aqueous Buffer Solution

At least 6 months at –80°C.

1. Chen L., et al. Front Biosci. 2005. 296(1)10: 1961-1976.

2.  Mhawech., et al. Eur.J.Surg.Oncol; 2006. 32(2): 231-237.

Avoid freeze/thaw cycles. Storing diluted enzyme is not recommended, if necessary, use carrier protein (BSA 0.1 – 0.5%).

Kinase

Protein