产品名称 Rat CD38 Inhibitor Screening Assay Kit (Hydrolase Activity) - Immunotherapy
产品货号 79690
产品价格 现货询价,电话:010-67529703
产品规格 96 rxns
产品品牌 bpsbioscience
产品概述
产品详情
Background:
CD38, a differentiation antigen of B lymphocytes, is a type II integral membrane protein that functions as an ADP-ribosyl cyclase and nicotinamide adenine dinucleotide (NAD) glycohydrolase. The major enzymatic activity of CD38 is the hydrolysis of NAD. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in various cells, including pancreatic  cells. CD38 is a prognostic biomarker for acute B lymphoblastic leukemia.
Description:
The Rat CD38 Inhibitor Screening Assay Kit (Hydrolase Activity) is designed to measure the glycohydrolase activity of rat CD38 for screening and profiling applications.
Materials Required But Not Provided:

Adjustable micropipettor and sterile tips
Fluorescent microplate reader
Rotating or rocker platform

Synonym(s):
Cluster of Differentiation, 38ADPRC1, ADPRC 1, CD38 molecule
Format:

Assay Kit Components

Instructions for use:
See assay protocol.
Storage / Stability:
Up to 6 months from date of receipt, when stored as recommended.
Application(s):
Great for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
Reference(s):

Koguma, T., et al. Biochim. Biophys. Acta Mol. Cell. Res. 1994. 1223(1): 160-162
Malavasi, F., et al. Physiol. Rev. 2008. 88(3): 841-886

Warning(s):
Avoid multiple freeze/thaw cycles
Scientific Category:
Immunotherapy
Product Type:
Assay Kit
Data shown is lot-specific. Contact us for specific information on other lots.

Quality Assurance

Product Datasheets

79690.pdf
产品资料