产品名称 | Rat CD38 Inhibitor Screening Assay Kit (Hydrolase Activity) - Immunotherapy |
产品货号 | 79690 |
产品价格 | 现货询价,电话:010-67529703 |
产品规格 | 96 rxns |
产品品牌 | bpsbioscience |
产品概述 | |
产品详情 |
Background: CD38, a differentiation antigen of B lymphocytes, is a type II integral membrane protein that functions as an ADP-ribosyl cyclase and nicotinamide adenine dinucleotide (NAD) glycohydrolase. The major enzymatic activity of CD38 is the hydrolysis of NAD. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in various cells, including pancreatic cells. CD38 is a prognostic biomarker for acute B lymphoblastic leukemia.
Description: The Rat CD38 Inhibitor Screening Assay Kit (Hydrolase Activity) is designed to measure the glycohydrolase activity of rat CD38 for screening and profiling applications.
Materials Required But Not Provided: Adjustable micropipettor and sterile tips Synonym(s): Cluster of Differentiation, 38ADPRC1, ADPRC 1, CD38 molecule
Format: Instructions for use: See assay protocol.
Storage / Stability: Up to 6 months from date of receipt, when stored as recommended.
Application(s): Great for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
Reference(s): Koguma, T., et al. Biochim. Biophys. Acta Mol. Cell. Res. 1994. 1223(1): 160-162 Warning(s): Avoid multiple freeze/thaw cycles
Scientific Category: Immunotherapy
Product Type: Assay Kit
Data shown is lot-specific. Contact us for specific information on other lots.
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