产品名称 ICSOL - CHO Recombinant Cell Line - BPS Bioscience
产品货号 79635
产品价格 现货询价,电话:010-67529703
产品规格 2 vials
产品品牌 bpsbioscience
产品概述
产品详情
Background:
ICOSL is the Ligand for the T-cell-specific cell surface receptor ICOS. When engaged by the ICOSL, the ICOS initiates a costimulatory signal for T-cell proliferation and cytokine production. It also induces B-cell proliferation and differentiation into plasma cells. The ICOS/ICOSL is a major regulator of the adaptive immune responses and also plays an important role in mediating local tissue responses to inflammatory conditions.
Description:
Recombinant CHO-K1 cells constitutively expressing human ICOSL (also known as human secreted B7 homolog 2 (B7-H2), CD275, ICOSLG, and B7-related protein (B7RP), GenBank Accession No. NM_001283050.
Synonym(s):
B7 homolog 2, CD275, ICOSL, ICOSLG, B7-related protein (B7RP), B7-H2
Supplied As:
Each vial contains ~ 2 x 10^6 cells in 1 ml of 10% DMSO.
Host Cell line:
CHO, Chinese Hamster Ovary
Mycoplasma Testing:
This cell line has been screened using the MycoAlert™ Mycoplasma Detection Kit (Lonza, #LT07-118) to confirm the absence of Mycoplasma contamination.
Growth Media:

Thaw Medium 3 (BPS Bioscience #60186): Ham’s F-12 medium (Hyclone #SH30526.01) supplemented with 10% FBS (Life technologies #26140-079), 1% Penicillin/Streptomycin (Hyclone #SV30010.01).

Growth Medium 3D (BPS Bioscience #79539): Thaw Medium 3 (BPS Bioscience #60186) plus 1 mg/ml of Geneticin (Life Technologies #11811031) to ensure recombinant expression.

Instructions for use:
See data sheet for detailed culturing and assay protocol.
Storage / Stability:
Store in liquid nitrogen immediately upon receipt.
Application(s):
This cell line is useful for screening for ICOSL antibodies through flow cytometry, immunocytochemistry or Western blot.
Notes:

License Disclosure: Purchase of this cell line grants you with a 10-year license to use this cell line in your immediate laboratory, for research use only. This license does not permit you to share, distribute, sell, sublicense, or otherwise make the cell line available for use to other laboratories, departments, research institutions, hospitals, universities, or biotech companies. The license does not permit the use of this cell line in humans or for therapeutic or drug use. The license does not permit modification of the cell line in any way. Inappropriate use or distribution of this cell line will result in revocation of the license and result in an immediate cease of sales and distribution of BPS products to your laboratory. BPS does not warrant the suitability of the cell line for any particular use, and does not accept any liability in connection with the handling or use of the cell line. Modifications of this cell line, transfer to another facility, or commercial use of the cells may require a separate license and additional fees; contact sales@bpsbioscience.com for details. Publications using this cell line should reference BPS Bioscience, Inc., San Diego.

Warning(s):
Avoid freeze/thaw cycles.
Scientific Category:
Immunotherapy
Product Type:
Cell Line
Data shown is lot-specific. Contact us for specific information on other lots.

Quality Assurance

Product Datasheets

79635.pdf
产品资料