SIRP alpha protein, or Signal regulatory proteinalpha (SIRP-α), also known as Tyrosine protein phosphatase non-receptor type substrate 1, CD172a, Bit, and MyD-1, GenBank Accession No. NM_080792, a.a. 27-370, with C-terminal Avi and His tags, MW 40.3 kDa*, expressed in a HEK293 expression system and enzymatically biotinylated using Avi-tag™ technology. This SIRP alpha protein acts as a receptor for CD47; a.a. 27-370 correspond to the extracellular portion of SIRP-α. *Note: SIRP-α is heavily glycosylated, resulting in higher molecular weight.
| 产品名称 | SIRP alpha protein |
| 产品货号 | 71138 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 50 µg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
Species: HEK293
Host Species: Human
MW: 40.3 kDa
Genbank #: NM_080792
Tag(s): C-terminal His-Avi-Tags
a.a: 27-370
Description: UniProt P78324
Synonym(s): SIRP alpha protein, sirpa protein, sirp-a protein, SIRPα, CD172a, Tyrosine-protein phosphatase non-receptor type substrate 1, CD172a, Bit, and MyD-1
Formulation: 8 mM Phosphate, pH 7.4,
110 mM NaCl, 2.2 mM KCl, and 20%
glycerol
Format: Aqueous buffer solution
Storage / Stability: At least 6 months at –80°C
Application(s): Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Reference(s): 1. Hatherley, D., et al., Mol. Cell, 2008, 31:266-77 Notes: HiP™ indicates a high purity protein with ≥90% purity as measured by gel filtration. Warning(s): Avoid freeze/thaw cycles. Protein may be diluted to ≥ 100 μg/ml in PBS + glycerol and stored at -80°C.
Scientific Category: Immunotherapy
Product Type: Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
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