Human TIM-3, also known as T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, TIMD-3, Hepatitis A virus cellular receptor 2, HAVCR-2, and KIM- 3. GenBank Accession No. NM_032782, a.a. 22-200 with a C-terminal Avi-biotin, Histag, expressed in a HEK293 cell expression system. MW = 23.3 kDa. This protein is enzymatically biotinylated using Avi-tagTM technology. Biotinylation is confirmed to be greater than 90%. This protein runs at a higher MW by SDS-PAGE due to glycosylation.

Q8TDQ0

T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, TIMD-3, Hepatitis A virus cellular receptor 2, HAVCR-2, and KIM- 3

8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol

Aqueous buffer solution

At least 6 months at -80°C.

1. Zhu, C. et al., Nat. Immunol. 2005; 6:1245-1252.
2. Anderson, A.C. et al., Science. 2007; 318(5853):1141-1143.

HiP™ indicates a high purity protein with ≥90% purity as measured by gel filtration.

Avoid freeze/thaw cycles. Protein may be diluted to 100 μg/ml in PBS + glycerol and stored at -80°C.

Immunotherapy

Recombinant Protein