Histone H3 peptide (a.a. 1-21), tri-methylated at Lysine 9 with a C-terminal GG linker followed by a biotinylated Lys at its C-terminus.

H3K9me3, Histone H3 Lys9me3

≥90% by HPLC

40 µM in water (500 µl)

Aqueous buffer solution

At least 6 months from date of receipt, when stored as directed

Study enzyme kinetics, and screen small molecular inhibitors of JMJ for drug discovery and HTS applications

1. Grewal, S., et al., Curr Opin Cell Biol. 2004;16:230.
2. Rice, J., et al., Mol Cell. 2003;12: 1591.

Avoid freeze/thaw cycles.

ARTKQTAR-K(Me3)-STGGKAPRKQLA-GGK(Biotin)

Methyltransferase

Substrate