Human CD48, Fc fusion protein, also known as Cluster of Differentiation 48, BLAST-1, or SLAMF2. GenBank Accession No. NM_001778, a.a. 27-220 expressed in a HEK293 cell expression system. This protein is fused at the C-terminus to the Fc region of human IgG1 and is enzymatically biotinylated using Avi-tag™ technology. MW = 51 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.

Cluster of Differentiation 48, BLAST-1, SLAMF2

8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.

At least 6 months at –80°C. Avoid freeze/thaw cycles. Protein may be diluted to ≥ 100 µg/ml in PBS + glycerol and stored at -80°C.

Useful for studying protein binding and screening small molecules.

1. Nakajima, H. et al., European Journal of Immunology. 1999; 29(5): 1676-1683.

2. Brown, M.H., et al., Journal of Experimental Medicine. 1998; 188(11): 2083.

HiP™ indicates a high purity protein with ≥90% purity as measured by gel filtration.

This protein runs at a higher MW by SDS-PAGE due to glycosylation.

Avoid freeze/thaw cycles. Protein may be diluted to ≥ 100 µg/ml in PBS + glycerol and stored at -80°C.

Immunotherapy

Fc Fusion Protein