Human secreted CD2-Fc fusion protein, also known as LFA-2, GenBank Accession No. NM_001767, a.a. 25-209, fused at the C-terminus to the Fc portion of human IgG1, with C-terminal Avi-tag, expressed in a HEK293 cell expression system. MW = 50 kDa (monomer). This protein runs at a higher M.W. by SDS-PAGE due to glycosylation.

LFA-2

8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol

At least 6 months at –80°C. Avoid freeze/thaw cycles. Protein may be diluted to ≥ 100 µg/ml in PBS + glycerol and stored at -80°C.

Useful for the study of protein-protein interaction and in vitro and in vivo protein function studies.

1. Seed, B., et al., Nature. 1987 Oct; 329: 840-842.

2. Seed, B., et al., PNAS. 1987 May; 84: 3365-3369.

HiP™ indicates a high purity protein with >90 percent purity by gel filtration. This protein runs at a higher MW by SDS-PAGE due to glycosylation.

Avoid freeze/thaw cycles. Protein may be diluted to ≥ 100 µg/ml in PBS + glycerol and stored at -80°C.

Immunotherapy

Fc Fusion Protein