Human CD111, also known as Poliovirus receptor-related 1, netcin-1, herpesvirus entry mediator C, and HVEC. GenBank Accession No. NM_002855, a.a. 31-355, fused at the C-terminus to the Fc portion of Human IgG1 and with a C-terminal Avi-tag, expressed in a Hek293 cell expression system. This protein is enzymatically biotinylated using AviTag™ technology. MW=65 kDa.

NECTIN1, CD111, CLPED1, ED4, HIgR, HV1S, HVEC, OFC7, PRR, PRR1, PVRR, PVRR1, SK-12, nectin-1, PVRL1, nectin cell adhesion molecule 1

8 mM Phosphate, pH 7.4, 400 mM NaCl, 2.2 mM KCl, and 20% glycerol.

Aqueous buffer solution.

At least 6 months at –80°C.

1. Friedman, G., et al., Neuro-Oncology. 2009; 95(2); 199-209.

2. Waters, A., et al., Transitional Oncology. 2016; 9(5): 419-430.

HiP™ indicates a high purity protein with ≥90% purity as measured by gel filtration.

Avoid freeze/thaw cycles. Protein may be diluted to ≥ 100 µg/ml in PBS + glycerol and stored at -80°C. Storing diluted enzyme is not recommended, if necessary, use carrier protein (BSA 0.1 – 0.5%).

Immunotherapy

Recombinant Protein