| 产品名称 | ROR1, Fc-Fusion (IgG1), Avi-Tag, Biotin-Labeled - Other Biotinylated Products - Biotinylation |
| 产品货号 | 79482 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 50 µg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
Species: Human
Host Species: HEK293
MW: 71kDa
Genbank #: NM_005012
Tag(s): C-terminal Fc-Avi-Tag
a.a: 24-403
Background: ROR1 is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors that play a role in the control of most basic cellular processes including cell proliferation, differentiation, migration and metabolism. Many human breast cancers express the ROR1 protein and high-level expression of ROR1 in breast adenocarcinoma is associated with aggressive disease. Silencing expression of ROR1 in human breast cancer cell lines found to express this protein impaired their growth in vitro and also in immune-deficient mice.
Description: Human ROR1, also known as receptor tyrosine kinase-like orphan receptor 1, neurotrophic tyrosine kinase, and receptor-related 1 (NTRKR1), GenBank Accession No. NM_005012, a.a 24-403, with C-terminal Avi-TagTM fused to the Fc portion of Human IgG1 and expressed in a HEK293 cell expression system. MW = 71 kDa. This protein runs at a higher apparent M.W. by SDS-PAGE due to glycosylation. This protein is enzymatically biotinylated using Avi-TagTM technology. Synonym(s): receptor tyrosine kinase-like orphan receptor 1, neurotrophic tyrosine kinase, receptor-related 1 NTRKR1
Formulation: 8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol
Format: Aqueous buffer solution
Storage / Stability: At least 6 months at –80°C
Reference(s): 1. Fukuda, T., et al., PNAS. 2007 Dec; 105(8): 3047-3052. 2. Hudecek, M., et al., Clinical Cancer Research. 2013 Jun; 19(12): 3109. Notes: HiP™ indicates a high purity protein with ≥90% purity as measured by gel filtration. This protein runs at a higher apparent M.W. by SDS-PAGE due to glycosylation. This protein is enzymatically biotinylated using Avi-TagTM technology. Warning(s): Avoid freeze/thaw cycles.
Scientific Category: Cell Surface Receptor
Product Type: Protein
Data shown is lot-specific. Contact us for specific information on other lots.
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