Human Heat Shock Protein 90 beta (HSP90β), GenBank Accession No. NM_001271969, a.a. 527-724 (end) with N-terminal His-tag and N-terminal Avi-tag™, MW = 25 kDa, expressed in an E. coli expression system and enzymatically biotin-labeled using Avi-tag™ technology.

P08238

Hsp90beta, heat shock protein 90 beta

HSP90β (C-terminal):PPID binding activity measured using HSP90β (C-terminal) Inhibitor Screening Assay Kit, BPS Bioscience, Catalog # 50314.

40 mM Tris-HCl pH 8, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20, 20% glycerol

Aqueous buffer solution

>6 months at -80°C

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

1. Milicevic, Z. et al., Int. J. Oncol. 2008 Jun;32(6):1169-78.
2. Chao, C.C. et al., J. Cell Biochem. 2008 Jul 1;104(4):1286-96.

Application Reference(s):
1. Design, Synthesis, and Biological Activities of Vibsanin B Derivatives: A New Class of HSP90 C-Terminal Inhibitors (2017)

Avoid freeze/thaw cycles.

Heat Shock Proteins

Recombinant Protein