This peptide is histone H4 (1-23) monomethylated at Arg3 followed by a biotinylated Lys conjugated to a C-terminal GG linker. Methylation of Arg3 is catalyzed by PRMT1 and functions to promote p300 acetylation of histone H4. Provided at >95% peptide purity.

P62805

% Peak Area By HPLC ≥ 95%

200 uM solution in 200 ul of water

-20°C

Useful as a substrate for arginine methyltransferases and for screening small molecular inhibitors of Histone 4 (R3) methyltransferases for drug discovery."

Wang, H. et al. Science 293, 853 (2001).

Avoid freeze/thaw cycles

SG-R(Me1)-GKGGKGLGKGGAKRHRKVLRGG-K(Biotin)