Mouse TIM-3, also known as T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, TIMD-3, Hepatitis A virus cellular receptor 2, HAVCR-2, and KIM-3. GenBank Accession No. NM_032782, a.a. 22-191, expressed in a HEK293 cells expression system. This protein is fused at the C-terminus to the Fc region of human IgG1 and is enzymatically biotinylated using Avi-tag™ technology. MW = 47 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.

T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, TIMD-3, Hepatitis A virus cellular receptor 2, HAVCR-2, KIM-3

8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.

Aqueous buffer solution.

>6 months at –80°C.

1. Zhu, C. et al., Nat. Immunol. 2005; 6:1245-1252.
2. Anderson, A.C. et al., Science. 2007; 318(5853):1141-1143.

HiP™ indicates a high purity protein with ≥90% purity as measured by gel filtration.

Avoid freeze/thaw cycles. Protein may be diluted to ≥ 100 µg/ml in PBS + glycerol and stored at -80°C.

Immunotherapy

Recombinant Protein