| 产品名称 | PCGF6, GST-tag - Proteins - Other Proteins |
| 产品货号 | 55016 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 50 µg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
Host Species: Sf9 insect cells
MW: 65.7 kDa
Genbank #: NM_001011663.1
Tag(s): N-terminal GST-tag
a.a: 2–350 (end)
Background: Transcriptional repressor that modulates the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A Lys-119, rendering chromatin heritably changed in its expressibility.
Description: Human Polycomb group RING finger protein 6 (PCGF6), GenBank Accession No. NM_001011663, a.a. 2-350 (end), with N-terminal GST-tag, MW=65.7 kDa, expressed in a baculovirus expression system.
UniProt Q9BYE7
Synonym(s): Polycomb group RING finger protein 6, PCGF6, Mel18 And Bmi1-Like RING Finger Protein, MBLR, RNF134
Formulation: 40 mM Tris. pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20, and 20% glycerol.
Format: Aqueous buffer solution
Storage / Stability: ≥ 6 months at -80°C Application(s): Useful for protein binding assays, screening inhibitors, and selectivity profiling.
Reference(s): 1. Junco SE, et al.,Structure. 2013; Warning(s): Avoid freeze/thaw cycles
Scientific Category: Miscellaneous
Product Type: Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
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