| 产品名称 | CBX2, GST-tag |
| 产品货号 | 55011 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 100 µg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
Species: Human
Host Species: E. coli
MW: 37.3 kDa
Genbank #: NM_005189
Tag(s): N-terminal GST-tag
a.a: 2–90
Background: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A Lys119, rendering chromatin heritably changed in its expressibility. Involved in sexual development, acting as activator of NR5A1 expression.
Description: Human chromobox homolog 2 (CBX2), also known as SRXY5 and cell division cycle associated 6 (CDCA6), GenBank Accession No. NM_005189, a.a. 2-90, with N-terminal GST-tag, MW=37.3 kDa, expressed in an E. coli cell expression system.
UniProt Q14781
Synonym(s): chromobox homolog 2,CBX2, SRXY5, cell division cycle associated 6, CDCA6
Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 16 mM glutathione, 20% glycerol.
Format: Aqueous buffer solution
Storage / Stability: ≥ 6 months at -80°C Application(s): Useful for protein binding assays, screening inhibitors, and selectivity profiling.
Reference(s): 1. Völkel, P., et al., Epigenetics. 2012 Warning(s): Avoid freeze/thaw cycles
Scientific Category: Methyl-lysine Reader
Product Type: Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
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