产品名称 Otub1, His-tag - Deubiquitylating Enzymes - Ubiquitination
产品货号 81088
产品价格 现货询价,电话:010-67529703
产品规格 25 µg
产品品牌 bpsbioscience
产品概述
产品详情
Species: Human
Host Species: E. coli
MW: 32 kDa
Tag(s): His-tag
Background:
Otubain 1 is a member of the OTU (ovarian tumor) class of ubiquitin isopeptidases. It was originally identified as a protein capable of binding ubiquitin aldehyde.Researchers have shown that it is able to cleave K48-linked ubiquitin chains in vitro.Otubain 1 has been shown to be involved in T cell function and is a substrate for Yersinia protein kinase.
Description:
Human Otub1 recombinant protein, with His-tag, expressed in E. coli.
UniProt
Q96FW1
Synonym(s):
Deubiquitinating enzyme OTUB1, FLJ20113, FLJ40710, HSPC263, MGC111158, OTB1, OTU1, Otubain 1, OTU domain-containing ubiquitin aldehyde-binding protein 1, Ubiquitin-specific-processing protease OTUB1, Ubiquitin thioesterase protein OTUB1
Purity:
≥95% by SDS-PAGE
Format:
Aqueous buffer solution
Storage / Stability:

Store at or below –80°C. Stable as supplied for up to 1 year when stored dessicated at –80°C.

Application(s):
This enzyme cleaves K48- and K63- linked ubiquitin chains in vitro.
Reference(s):
1. Juris, S.J., et al. FEBS Lett. 2006. 581(1):179-183.
2. Soares, L., et al. Nat. Immunol. 2004. 51(1):45-54.
3. Balakirev, M. et al. EMBO Rep. 2003. 4(5): p517-522.
Warning(s):
Avoid freeze/thaw cycles.
Scientific Category:
Deubiquitinase
Product Type:
Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.

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