| 产品名称 | PTPσ (PTPRS), GST-tag - Protein Phosphatase(s) |
| 产品货号 | 30045 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 20 µg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
Species: Human
Host Species: E. coli
MW: 98 kDa
Genbank #: BC104812
Tag(s): N-terminal GST-tag
a.a: 883–end
Background: PTPRS is a member of a subfamily of receptor type PTPases that is characterized by the presence of an extracellular cell adhesion molecule-like motif and 2 intracellular phosphatase domains. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis.
Description: Human PTPRS (GenBank Accession No. BC104812), a.a. 883-end, with N-terminal GST-tag, MW= 98 kDa, expressed in an E. coli expression system.
Synonym(s): PTPsigma, PTPRS, protein tyrosine phosphatase sigma, PTPσ
Specific Activity: 347 pmol/min/µg
Assay Conditions: 20 mM HEPES, pH 7.2, 2 mM EDTA, 1 mM DTT, 25 mM pNPP. Assay was done at room temperature
for 16 minutes, and monitored continuously at Abs405 nM. ε pNPP = 18,000 M-1cm-1.
Formulation: 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 20% glycerol, and 3 mM DTT.
Format: Aqueous buffer solution
Storage / Stability: >12 months at -80°C. Application(s): Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Reference(s): 1. Forrest, A.R. et al., Genome Biol. 2006;7(1):R5.
2. Muise, A. and Rotin, D. Expert Rev Mol. Diagn. 2008 Jul;8(4):465-77. Warning(s): Avoid freeze/thaw cycles
Scientific Category: PTP/Receptor
Product Type: Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
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