| 产品名称 | FAP, His-tag - Enzymes - Protease(s) |
| 产品货号 | 80100 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 25 µg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
Species: Human
Host Species: Sf9 insect cells
MW: 85.5 kDa
Genbank #: NM_004460
Tag(s): C-terminal His-tag
a.a: 29–end
Background: Fibroblast Activation Protein, or FAP, is a 170 kDa dimer with
dipeptidase activity. FAP expression is seen on activated stromal fibroblasts in >90% of
all human carcinomas, suggesting a role in the development, growth and metastasis of
carcinomas. It is also involved in the control of wound healing and tissue repair.
Description: Human FAP (GenBank Accession No. NM_004460), (a.a. 29-end) with C-terminal His-tag, MW=85.5 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
UniProt Q12884
Synonym(s): Fibroblast Activation Protein, seprase
Specific Activity: ≥ 83 pmol/min/µg.
Assay Conditions: 50 mM Tris-HCl (pH 7.5),
10 mM MgCl2, 1 mM MnCl2, 5 µM
substrate (A-P-AMC), incubation 10 min at
room temperature.
Formulation: 40 mM Tris-HCl, pH 8.0,
110 mM NaCl, 2.2 mM KCl, 200 mM
imidazole, and 20% glycerol.
Format: Aqueous buffer solution
Storage / Stability: >6 months at -80°C. Application(s): Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Reference(s): 1. Edosada,C.Y. et al., J. Biol. Chem. 281 (11),
7437-7444 (2006).
2. Edosada,C.Y. et al., FEBS Lett. 580 (6), 1581-1586 (2006). Warning(s): Avoid freeze/thaw cycles
Scientific Category: Protease
Product Type: Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
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| 产品资料 |
