| 产品名称 | DPP7, His-tag - Enzymes - Protease(s) |
| 产品货号 | 80070 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 10 µg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
Species: Human
Host Species: Sf9 insect cells
MW: 53 kDa
Genbank #: NM_013379
Tag(s): C-terminal His-tag
a.a: 26–end
Background: Dipeptidyl peptidase-7 (DPP7), also known as DPP2, is a serine
aminopeptidase found in quiescent lymphocytes. Inhibition of this enzyme induces
apoptosis, and levels of DPP7 are elevated in many tumors, suggesting that DPP7 may be
involved in a novel pathway for tumor suppression.
Description: Human DPP7 (GenBank Accession No. NM_013379), a.a. 26-end with C-terminal His-tag, MW=52.5 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
UniProt Q9UHL4
Synonym(s): Dipeptidylpeptidase 7, QPP, Carboxytripeptidase, DPP2, DPP
Specific Activity: ≥ 1880 pmol/min/µg.
Assay Conditions: Test wells contained 0.01M Tris-HCl pH7.4, 0.01M MgCl2, 0.05% Tween-20, 5 µM DPP substrate 1, and various amounts of DPP7(0-200ng). Standard wells contained 0.01M Tris-HCl pH7.4, 0.01M MgCl2, 0.05% Tween-20, and various amounts of Fluorescent AMC standard (0.01 µM-1.25 µM). Incubated for 10 minutes at room temperature. Fluorescence intensity was measure at excitation 360 nm and emission 460 nm.
Formulation: 40 mM Tris-HCl, pH 8.0,
110 mM NaCl, 2.2 mM KCl, 220 mM imidazole,
and 20% glycerol
Format: Aqueous buffer solution
Storage / Stability: >6 months at -80°C. Application(s): Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Reference(s): 1. Shreder K.R. et al., Bioorg Med Chem
Lett. 2005 Oct 1;15(19):4256-60.
2. Maes M.B. et al., Biochem J. 2005 Mar 1;386(Pt 2):315-24. Warning(s): Avoid freeze/thaw cycles
Scientific Category: Protease
Product Type: Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
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