| 产品名称 | Irsogladine - Inhibitors / Activators - Phosphodiesterase(s) |
| 产品货号 | 27754 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 50 mg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
MW: 256.1 Da
CAS Registry #: 57381-26-7
Formula: C9H7Cl2N5
Target: PDE4
Background: Irsogladine is a selective PDE4 inhibitor that facilitates gap junction intercellular communication through muscarinic acetylcholine receptor binding. It is a potent inhibitor of angiogenesis in wild-type and plasminogen activator-deficient mice. Inhibition of PDE4 prevents the hydrolysis of cAMP, an important secondary messenger molecule that is heavily involved in signal transduction.
Description: Phosphodiesterase 4 (PDE4) inhibitor that displays gastroprotective properties. Prevents gastric mucosal injury induced by monochloramine and ischemia-reperfusion. Activates gap-junctional intercellular communication improving gastric mucosal barrier function. Inhibits superoxide production in human neutrophils and inhibits in vitro and in vivo angiogenesis.
Synonym(s): MN 1695; 6-(2,5-Dichlorophenyl)-1,3,5-triazine-2,4-diamine maleate
Solubility: Soluble in DMSO
Format: White crystalline powder
Storage / Stability: Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day. Scientific Category: PDE Inhibitor
Product Type: Inhibitor
Data shown is lot-specific. Contact us for specific information on other lots.
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