产品名称 Cilomilast - Inhibitors / Activators - Phosphodiesterase(s)
产品货号 27742-2
产品价格 现货询价,电话:010-67529703
产品规格 10 mg
产品品牌 bpsbioscience
产品概述
产品详情
MW: 343.4 Da
CAS Registry #: 153259-65-5
Formula: C20H25NO4
Target: PDE4
Description:
Cilomilast, also known as SB-207499 or Ariflo, is a potent second generation inhibitor of type 4 phosphodiesterase (PDE4), an enzyme metabolizing cellular cyclic adenosine monophosphate (cAMP) which acts as a second messenger to disrupt the function of inflammatory cell and induce airway smooth muscle relaxation.
Synonym(s):
Cilomilast; SB-207499; Ariflo
Solubility:
Soluble in DMSO
Storage / Stability:

Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.

Reference(s):
1. M Profita, et al. Thorax 2003; 58: 573-579.
2. Barry D. et al. J Clin Pharmacol 2001; 41: 950-958.
Scientific Category:
PDE Inhibitor
Product Type:
Inhibitor
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