产品名称 | Cilomilast - Inhibitors / Activators - Phosphodiesterase(s) |
产品货号 | 27742-1 |
产品价格 | 现货询价,电话:010-67529703 |
产品规格 | 5 mg |
产品品牌 | bpsbioscience |
产品概述 | |
产品详情 |
MW: 343.4 Da
CAS Registry #: 153259-65-5
Formula: C20H25NO4
Target: PDE4
Description: Cilomilast, also known as SB-207499 or Ariflo, is a potent second generation inhibitor of type 4 phosphodiesterase (PDE4), an enzyme metabolizing cellular cyclic adenosine monophosphate (cAMP) which acts as a second messenger to disrupt the function of inflammatory cell and induce airway smooth muscle relaxation.
Synonym(s): Cilomilast; SB-207499; Ariflo
Solubility: Soluble in DMSO
Storage / Stability: Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day. Reference(s): 1. M Profita, et al. Thorax 2003; 58: 573-579.
2. Barry D. et al. J Clin Pharmacol 2001; 41: 950-958. Scientific Category: PDE Inhibitor
Product Type: Inhibitor
Data shown is lot-specific. Contact us for specific information on other lots.
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产品资料 |