The fluorogenic PDE substrate FAM-cAMP is used for cAMP-dependent phosphodiesterase assays. It has been used in activity assays for PDE1, PDE2, PDE3, PDE4, PDE7, PDE8, PDE10 and PDE11.

1 {2'-(6-[Fluoresceneinyl] aminohexylcarbamoyl)adenosine-3',5'-cyclic monophosphate}

≥95% by HPLC

1 mM aqueous solution

Store at -20°C. Stability: At least 6 months from date of receipt, when stored as directed

Useful for assaying phosphodiesterase activity, and for screening of small molecule inhibitors for drug discovery and HTS applications.

Avoid freeze/thaw cycles.

PDE

Substrate