产品名称 Cilostazol - Phosphodiesterase(s)
产品货号 27743-2
产品价格 现货询价,电话:010-67529703
产品规格 100 mg
产品品牌 bpsbioscience
产品概述
产品详情
MW: 369.5 Da
CAS Registry #: 73963-72-1
Formula: C20H27N5O2
Target: PDE3
Background:
Cilostazol (OPC-13013, Pletal) is a 2-oxo-quinoline derivative with antithrombotic, vasodilator, antimitogenic and cardiotonic properties. Cilostazol is used in the treatment of peripheral arterial disease and claudication (leg cramps). Cilostazol inhibits platelet aggregation and is a direct arterial vasodilator.
Description:
Cilostazol is a potent cyclic nucleotide phosphodiesterase type 3 (PDE3) inhibitor with IC50 of 0.2 µM and inhibitor of adenosine uptake.
Synonym(s):
Pletal; OPC-13013
Solubility:
Soluble in DMSO (18 mg/ml).
Format:
white to off-white crystals
Storage / Stability:

Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.

Reference(s):
1. Cone J, et al. J Cardiovasc Pharmacol, 1999, 34(4), 497-504.
2. Liu Y, et al. Cardiovasc Drug Rev, 2001, 19(4), 369-386.
Scientific Category:
PDE Inhibitor
Product Type:
Inhibitor
Data shown is lot-specific. Contact us for specific information on other lots.

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