Human Histone 2A, GenBank Accession No. NM_033445, a.a. 2-130(end) with N-terminal His-tag, MW = 14.8 kDa, expressed in an E. coli expression system.

Q7L7L0

HIST1H2AI, H2A.1, histone H2A

50 mM Tris-HCl, pH 8.0, 150 mM NaCl, 10% glycerol, 1 mM PMSF and 1 mM DTT.

Aqueous buffer solution

>6 months at –80°C.

Useful as a substrate for histone methyltransferase and acetyltransferase assays. Ideal for screening small molecular inhibitors of histone modifying enzymes for drug discovery and HTS applications.

1.   Osley,  M.A.  Brief  Funct.  Genomic 
Proteomic 5(3):179-89 (2006). 
2.  Wyrick,  J.J.  and  Parra,  M.A..  Biochim 
Biophys Acta. 1789(1):37-44 (2009). 
3.  Zhou, W.,  et  al.  Int  J  Biochem  Cell  Biol. 
41(1):12-5  (2009).

Avoid freeze/thaw cycles

Methyltransferase/Substrate

Recombinant Protein