| 产品名称 | Histone H1, Full Length, His-tag - Substrates - Methyltransferase(s) |
| 产品货号 | 52042 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 1 mg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
Species: Human
Host Species: E. coli
MW: 22 kDa
Genbank #: NM_005318
Tag(s): N-terminal His-tag
a.a: 2–194(end)
Background: Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.
Description: Human Histone H1, also known as H1F0, (GenBank Accession No. NM_005318), a.a. 2-194(end) with N-terminal His-tag, MW = 21.7 kDa, expressed in an E. coli expression system.
UniProt P07305
Synonym(s): Histone H1, H1F0
Formulation: 8 mM PBS pH 7.4, 110 mM NaCl, 2.2 mM KCl, 3 mM DTT, and 20% glycerol.
Format: Aqueous buffer solution
Storage / Stability: >6 months at –80°C. Application(s): Useful as a substrate for histone methyltransferase and acetyltransferase assays. Ideal for screening small molecular inhibitors of histone modifying enzymes for drug discovery and HTS applications.
Reference(s): 1. Doenecke, D., et al., J. Mol.Biol. 1986 Warning(s): Avoid freeze/thaw cycles
Amino Acid Sequence: MHHHHHHTENSTSAPAAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKPKKAKPVKPKAKSSAKRAGKKK
Scientific Category: Methyltransferase/Substrate
Product Type: Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
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