产品名称 | DDR2, GST-tag - Kinase Receptor Tyrosine - Kinase(s) |
产品货号 | 40185 |
产品价格 | 现货询价,电话:010-67529703 |
产品规格 | 10 µg |
产品品牌 | bpsbioscience |
产品概述 | |
产品详情 |
Species: Human
Host Species: Sf9 insect cells
MW: 70 kDa
Genbank #: NM_006182
Tag(s): N-terminal GST-tag
a.a: 467–end
Background: DDR2 is a member of a novel subclass of RTKs containing a distinct extracellular region encompassing a factor VIII-like domain (1) and is thought to be involved in the regulation of cell growth, differentiation, and metabolism. DDR2 plays a role in the regulation of collagen turnover mediated by smooth muscle cells in obstructive diseases of blood vessels and the lung (2).
Description: Recombinant human DDR2 (467-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST-tag. The gene accession number is NM_006182.
Synonym(s): TKT, NTRKR3, TYRO10
Purity: ≥90%
Specific Activity: 25 pmol/min/µg
Formulation: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Format: Aqueous buffer solution
Storage / Stability: >6 months at -80°C Application(s): Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Reference(s): 1. Karn, T. et al. Oncogene 8: 3433-3440, 1993.
2. Ferri, N. et al. Am J Pathol. 2004 May,164(5):1575-85. Warning(s): Avoid freeze/thaw cycles
Scientific Category: Kinase/Receptor Tyrosine
Product Type: Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
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产品资料 |