产品名称 DDR2, GST-tag - Kinase Receptor Tyrosine - Kinase(s)
产品货号 40185
产品价格 现货询价,电话:010-67529703
产品规格 10 µg
产品品牌 bpsbioscience
产品概述
产品详情
Species: Human
Host Species: Sf9 insect cells
MW: 70 kDa
Genbank #: NM_006182
Tag(s): N-terminal GST-tag
a.a: 467–end
Background:
DDR2 is a member of a novel subclass of RTKs containing a distinct extracellular region encompassing a factor VIII-like domain (1) and is thought to be involved in the regulation of cell growth, differentiation, and metabolism. DDR2 plays a role in the regulation of collagen turnover mediated by smooth muscle cells in obstructive diseases of blood vessels and the lung (2).
Description:
Recombinant human DDR2 (467-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST-tag. The gene accession number is NM_006182.
Synonym(s):
TKT, NTRKR3, TYRO10
Purity:
≥90%
Specific Activity:
25 pmol/min/µg
Formulation:
50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Format:
Aqueous buffer solution
Storage / Stability:

>6 months at -80°C

Application(s):
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Reference(s):
1. Karn, T. et al. Oncogene 8: 3433-3440, 1993.
2. Ferri, N. et al. Am J Pathol. 2004 May,164(5):1575-85.
Warning(s):
Avoid freeze/thaw cycles
Scientific Category:
Kinase/Receptor Tyrosine
Product Type:
Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.

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