| 产品名称 | BLK, GST-tag - Kinase Receptor Tyrosine - Kinase(s) |
| 产品货号 | 40401 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 10 µg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
Species: Human
Host Species: Sf9 insect cells
MW: 84 kDa
Genbank #: BC007371
Tag(s): N-terminal GST-tag
a.a: full length
Background: BLK, also known as B lymphoid kinase, is a 55 kd tyrosine kinases with a SH3, SH2 and catalytic domains that contain consensus sequences of the src protein tyrosine kinase family. BLK is expressed specifically in the B cell lineage and plays a role in signal transduction pathway that is restricted to B lymphoid cells (1). Stimulation of resting B-lymphocytes with antibodies to surface immunoglobulin (sIgD or sIgM) induces activation of BLK (2).
Description: Recombinant full-length human BLK was expressed by baculovirus in Sf9 insect cells using an N-terminal GST-tag. The gene accession number is BC007371.
Synonym(s): MGC10442
Purity: ≥90%
Specific Activity: 112 pmol/min/µg
Formulation: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol.
Format: Aqueous buffer solution
Storage / Stability: >6 months at -80°C Application(s): Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Reference(s): 1. Dymecki, SM. et al. Science. 1990 Jan 19;247(4940):332-6.
2. Burkhardt, AL. et al. Proc Natl Acad Sci USA. 1991 Aug 15;88(16):7410-4. Warning(s): Avoid freeze/thaw cycles
Scientific Category: Kinase/Cytoplasmic Tyr
Product Type: Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
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