| 产品名称 | GSK3α Assay Kit - Kinase Assay Kits - Kinase(s) |
| 产品货号 | 79698 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 96 reactions |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
Background: GSK3 (Glycogen synthase kinase) is a serine/threonine kinase which initially was found to phosphorylate and inactivate glycogen synthase in glycogen biosynthesis. It is an important regulator enzyme in many disease pathogeneses including cancer, immune disorders, metabolic disorders and neurological disorders like Alzheimer’s disease. Recently, GSK3α, one of the isoforms of GSK3, was identified as a key target in acute myeloid leukemia (AML).
Description: The GSK3α Assay Kit is designed to measure GSK3α activity for screening and profiling applications using Kinase-Glo® (Promega) as a detection reagent.
Materials Required But Not Provided: Kinase-Glo® Max Assay (Promega #V6071) Synonym(s): Glycogen Synthase Kinase 3 Alpha, GSK-3 Alpha, Serine/Threonine-Protein Kinase GSK3A
Contraindications: Keep final DMSO concentration below 1%
Format:
Instructions for use: See assay protocol.
Storage / Stability: Up to 6 months when stored as recommended.
Application(s): Useful for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
Reference(s): McCubrey JA., et al. Oncotarget 5(10): 2881-2911 (2014)
Warning(s): Avoid multiple freeze/thaw cycles.
Scientific Category: Kinase
Product Type: Assay Kit
Data shown is lot-specific. Contact us for specific information on other lots.
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